BDBM139295 US10858323, Compound 1::US8614223, 73

SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1

InChI Key InChIKey=LIIWIMDSZVNYHY-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 139295   

TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  219nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  158nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  218nMAssay Description:Inhibition of N-terminal GST-tagged HDAC3 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  218nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed